From: Kelly O’Sullivan
The ability to accurately test drugs and therapies for human use is a goal we desperately need to reach. Often animals are used to test drugs intended for human use, which not only puts them at risk but many times does not produce results helpful to making these remedies safer for us. At the same time drugs tested on human cells grown in a petri dish doesn’t exactly represent how those drugs will react in a living, breathing body.
Fortunately, a development made by Michigan engineers has taken a major step in drug testing by reproducing the heartbeat in a simplified gravity-driven microfluidic circuit. This new device performs operations that once required a large amount of peripheral equipment as well as a dedicated lab technician to run. Beyond that, the chip can execute multiple experiments at once as well as mimic a variety of heart rates. With the help of this microfluidic chip we could see the testing phases for new therapies drastically shortened, allowing newer, more effective medicines finding their way into patients much faster.
From: Nicole Fawcett
U-M Health System
Why do some cancer cells break away from a tumor and travel to distant parts of the body? A team of oncologists and engineers from the University of Michigan teamed up to help understand this crucial question.
In a paper published in Scientific Reports, researchers describe a new device that is able to sort cells based on their ability to move. The researchers were then able to take the sorted cells that were highly mobile and begin to analyze them on a molecular level.
Assistant Professor of Biomedical Engineering, Zhen Xu received the 2015 Frederic Lizzi Early Career Award from the International Society of Therapeutic Ultrasound (ISTU). Every year, Lizzi Award is given to a researcher at early stage of career who has achieved significant accomplishment and contribution to the field of therapeutic ultrasound.