Peer-Reviewed Manuscripts

  1. Yen-Ling Lin, Yasemin Yuksel Durmaz, Jacques E. Nor, and Mohamed E.H. ElSayed, "Synergistic combination of small molecule inhibitor and RNA interference against anti-apoptotic Bcl-2 protein in head and neck cancer cells", Molecular Pharmaceutics, provisionally accepted.

  2. Hosam G. Abdelhady, Yen-Ling Lin, Haiping Sun, and Mohamed E.H. ElSayed, "Visualizing the attack of RNase enzymes on dendriplexes and naked RNA using atomic force microscopy", PLOS One, 8(4): e61710. doi:10.1371/journal.pone.0061710m 2013. [PDF File]

  3. Scott H. Medina, Gopinath Tiruchinapally, Maxim V. Chevliakov, Yasemin Y. Durmaz, Rachell N. Stender, William D. Ensminger, Donna S. Shewach, and Mohamed E.H. ElSayed, "Targeting hepatic cancer cells with PEGylated dendrimers displaying N-acetylgalactosamine and SP94 peptide ligands", Advanced Healthcare Materials, DOI: 10.1002/adhm.201200408, 2013. [PDF File]

  4. Yasemin Y. Durmaz, Yen-Ling Lin, and Mohamed E.H. ElSayed, "Development of degradable, pH-sensitive, star vectors for enhancing the cytoplasmic delivery of nucleic acids", Advanced Functional Materials, DOI: 10,1002/adfm.201203762, 2013. [PDF File]

  5. Scott H. Medina, Maxim V. Chevliakov, Gopinath Tiruchinapally, Yasemin Y. Durmaz, Sibu Kuruvilla, and Mohamed E.H. ElSayed, "Development of enzyme-activated nano-conjugates for tunable release of chemotherapeutic agents in hepatic cancer cells", Biomaterials, 34(19): 4655-4666, 2013. [PDF File]

  6. Jack D. Wang, Nicholas J. Douville, Shuichi Takayama, and Mohamed E.H. ElSayed, "Quantitative analysis of molecular absorption into PDMS microfluidic channels", Annals of Biomedical Engineering, in press (DOI: 10.1007/s10439-012-0562-z). [PDF File]

  7. Scott H. Medina, Venkatesh Tekumalla, Maxim Chevliakov, Donna S. Shewach, William Ensminger, and Mohamed E.H. El-Sayed, "N-acetylgalactosamine-functionalized dendrimers as liver-targeted carriers", Biomaterials, 32:4118-4129, 2011. [PDF File]

  8. Stephanie Grainger, Juliana Valencia Serma, Steffi Sunny, Yun Zhou, Cheri X. Deng, and Mohamed E.H. El-Sayed, "Pulsed ultrasound enhances nanoparticle penetration into breast cancer spheroids", Molecular Pharmaceutics, 7(6): 2006-2019, 2010. (ASAP Article) [PDF File]

  9. Adam A. Dinerman, Joseph Cappello, Mohamed E.H. El-Sayed, Stephen W. Hoag, and Hamidreza Ghandehari, " Influence of solute charge and hydrophobicity on partitioning and diffusion in a genetically engineered silk-elastin like protein polymer hydrogel", Macromolecular Bioscience, 10:1235-1247, 2010.[PDF File]

  10. Jallal El Hazzat and Mohamed E.H. El-Sayed, "Advances in targeted breast cancer therapy", Current Breast Cancer Reports, 2:146-151, 2010. [PDF File]

  11. Yen-Ling Lin, Guohua Jiang, Lisa Birrell, and Mohamed E.H. El-Sayed, "Degradable, pH-sensitive, membrane-destabilizing, comb-like polymers for intracellular delivery of nucleic acids", Biomaterials, 31(27): 7150-7166, 2010. [PDF File]

  12. Juyoung Park, Zhenzhen Fan, Ronald E. Kumon, Mohamed E.H. El-Sayed, and Cheri X. Deng, "Modulation of intracellular calcium concentration in brain microvascular endothelial cells in vitro by acoustic cavitation", Ultrasound in Medicine and Biology, 36(7): 1176-1187, 2010. [PDF File]

  13. Nicholas J. Douville, Yi-Chung Tung, Ran Li, Jack Dong Wang, Mohamed E.H. El-Sayed, and Shuichi Takayama, "Fabrication of two-layered channel system with embedded electrodes to measure resistance across epithelial and endothelial barriers", Analytical Chemistry, 82(6): 2505-2511, 2010. [PDF File]

  14. Yen-Ling Lin, Khalil Khanafer, and Mohamed E.H. El-Sayed, "Quantitative evaluation of the effect of poly (amidoamine) dendrimers on the porosity of Caco-2 cell monolayers", Nanoscale, 2: 755-762, 2010. [PDF File]

  15. Stephanie Grainger, and Mohamed E.H. El-Sayed, "Stimuli-sensitive particles for drug delivery" in Biologically Responsive Hybrid Biomaterials, Esmaiel Jabbari and Ali Khademhosseini (Ed), Artech House, Boston, MA, USA, Pages: 171-190. [PDF File]

  16. Scott H. Medina, and Mohamed E.H. El-Sayed, "Dendrimers as Carriers for Delivery of Chemotherapeutic Agents", Chemical Reviews, 109: 3141-3157, 2009. [PDF File]

  17. Rachel Johns, Mohamed E.H. El-Sayed, Volga Bulmus, Joseph Cuschieri, Ronald Maier, Allan S. Hoffman, and Patrick S. Stayton, "Mechanistic Analysis of Macrophage Response to IRAK-1 Gene Knockdown by a Smart Polymer-Antisense Oligonucleotide Therapeutic", Journal of Biomaterial Science: Polymer Edition, 19(10): 1333-1346, 2008. [PDF File]

  18. Allan S. Hoffman, Patrick S. Stayton, Mohamed E.H. El-Sayed, Niren Murthy, Volga Bulmus, Chantal Lackey, Charles Cheung, "Design of smart nano-scale delivery systems for biomolecular therapeutics", Journal of Biomedical Nanotechnology, 3 (2): 213-217, 2007. [PDF File]

  19. Scott M. Henry, Mohamed E.H. El-Sayed, Christopher M. Pirie, Allan S. Hoffman, and Patrick S. Stayton, "pH-responsive poly(styrene-alt-maleic anhydride) alkylamide copolymers for intracellular drug delivery", Biomacromolecules, 7: 2407-2414, 2006. [PDF File]

  20. Kelly Kitchens, Mohamed E.H. El-Sayed, and Hamidreza Ghandehari, "Transepithelial and -endothelial transport of poly(amidoamine) dendrimers", Advanced Drug Delivery Reviews, 57 (15): 2163-2176, 2005. [PDF File]

  21. Patrick S. Stayton, Mohamed E.H. El-Sayed, Niren Murthy, Volga Bulmus, Chantal Lackey, Charles Cheung, and Allan S. Hoffman, "Smart delivery systems for biomolecular therapeutics", Orthodontics & Craniofacial Research, 8 (3): 219-225, 2005. [PDF File]

  22. Patrick S. Stayton, Allan S. Hoffman, Mohamed E.H. El-Sayed, Samarth Kulkarni, Tsuyoshi Shimoboji, Niren Murthy, Volga Bulmus, and Chantal Lackey, "Intelligent biohybrid materials for therapeutic and imaging agent delivery", Proceeding of the IEEE (Institute of Electrical and Electronics Engineers), 93 (4): 726-736, 2005. [PDF File]

  23. Mohamed El-Sayed, Allan S. Hoffman, and Patrick Stayton, "Smart polymeric carriers for enhanced intracellular drug delivery of therapeutic macromolecules", Expert Opinion on Biological Therapy, 5 (1): 23-32, 2005. [PDF File]

  24. Mohamed E.H. El-Sayed, Allan S. Hoffman, and Patrick S. Stayton, "Rational design of composition and activity correlations for pH-sensitive and glutathione-reactive polymer therapeutics", Journal of Controlled Release, 101 (1-3): 47-58, 2005. [PDF File]

  25. Mohamed El-Sayed, Mark Ginski, Christopher Rhodes, and Hamidreza Ghandehari, "Transport mechanism(s) of poly (amidoamine) dendrimers across Caco-2 cell monolayers", International Journal of Pharmaceutics, 265 (1-2): 151-157, 2003. [PDF File]

  26. Mohamed El-Sayed, Mark Ginski, Christopher Rhodes, and Hamidreza Ghandehari, "Influence of surface chemistry of poly (amidoamine) dendrimers on Caco-2 cell monolayers", Journal of Bioactive and Compatible Polymers, 18 (1): 7-22, 2003. [PDF File]

  27. Mohamed El-Sayed, Mark Ginski, Christopher Rhodes, and Hamidreza Ghandehari, "Transepithelial transport of poly (amidoamine) dendrimers across Caco-2 cell monolayers", Journal of Controlled Release, 81 (3): 355-365, 2002. [PDF File]

  28. Farhad Tajarobi, Mohamed El-Sayed, Bhagwant Rege, James Polli, and Hamidreza Ghandehari, "Transepithelial transport of poly (amidoamine) (PAMAM) dendrimers across Madin-Darby Canine Kidney (MDCK) cells", International Journal of Pharmaceutics, 215 (1-2): 263-267, 2001. [PDF File]

  29. Mohamed El-Sayed, Mohammad F. Kiani, Mike D. Naimark, Ahmed H. Hikal, and Hamidreza Ghandehari, "Extravasation of poly (amidoamine) (PAMAM) dendrimers across microvascular network endothelium", Pharmaceutical Research, 18 (1): 23-28, 2001. [PDF File]

Patents

  1. Patent Application Title: Targeted Dendrimer-Drug Conjugates; US Patent Application No. 61/258,811; Filed on December 16, 2009, Inventor: Mohamed E.H. El-Sayed, Donna S. Shewach, William Ensminger.

  2. Provisional Patent Application Title: Microfluidic system for measuring cell barrier function; Application No. 61445232; Filed on February 22, 2011; Inventors: Mohamed E.H. El-Sayed, Nicholas Douville, Yi-Chung Tung, Shuichi Takayama, Jack Dong Wang.

  3. Patent Application Title: Polymeric Nanoparticles for Ultrasound Imaging and Therapy; Application No. 61/545,418 and 61/545,898; Filed on October 10, 2011; Inventors: Mohamed E.H. El-Sayed, Yasemin Y. Durmaz.

Conference Proceedings

  1. M. E.H. ElSayed, S. H. Medina, S. Kuruvilla, G. Tiruchinapally, M. V. Chevliakov, and Y. Y. Durmaz, "Development of Targeted, Enzyme-Activated, Nano-Conjugates for Hepatic Cancer Therapy", Frontiers in Bioengineering Workshop, Georgia Tech-Parker H. Petit Institute for Bioengineering & Bioscience, February 25-26, 2013, Atlanta, Georgia.

  2. S. Kuruvilla, G. Tiruchinapally, S. Medina, and M. E.H. ElSayed, "Targeting hepatic cancer cells with PEGylated dendrimers displaying N-acetylgalactosamine and SP94 peptide ligands", Engineering Graduate Symposium, November 2, 2012, Ann Arbor, Michigan.

  3. Y-L. Lin, Y. Y. Durmaz, J. Nor, and M. E.H. ElSayed, "Development of smart particles for silencing Bcl-2 expression in head and neck cancer cells", Engineering Graduate Symposium, November 2, 2012, Ann Arbor, Michigan.

  4. Y. Y. Durmaz, E. Vlaisavljevich, Z. Xu, and M. E.H. ElSayed, "Development of nanodroplets for targeted ultrasound-mediated ablation of cancer", Engineering Graduate Symposium, November 2, 2012, Ann Arbor, Michigan.

  5. N. Kaushal, Y. Y. Durmaz, Y.-L. Lin, and M. E.H. ElSayed, "Development of targeted smart particles for silencing breast cancer metastases", Engineering Graduate Symposium, November 2, 2012, Ann Arbor, Michigan.

  6. S. Kuruvilla, G. Tiruchinapally, S. Medina, and M. E.H. ElSayed, "Targeting hepatic cancer cells with PEGylated dendrimers displaying N-acetylgalactosamine and SP94 peptide ligands", The 10th International Nanomedicine and Drug Delivery Symposium, October 29-30, 2012, Atlantic City, NJ, Proceedings.

  7. Y-L. Lin, Y. Y. Durmaz, J. Nor, and M. E.H. ElSayed, "Development of smart particles for silencing Bcl-2 expression in head and neck cancer cells", The 10th International Nanomedicine and Drug Delivery Symposium, October 20-30, 2012, Atlantic City, NJ, Proceedings.

  8. Y. Y. Durmaz, E. Vlaisavljevich, Z. Xu, and M. E.H. ElSayed, " Development of nanodroplets for targeted ultrasound-mediated ablation of cancer", The 10th International Nanomedicine and Drug Delivery Symposium, October 20-30, 2012, Atlantic City, NJ, Proceedings.

  9. N. Kaushal, Y. Y. Durmaz, Y.-L. Lin, and M. E.H. ElSayed, "Development of targeted smart particles for silencing breast cancer metastases", The 10th International Nanomedicine and Drug Delivery Symposium, October 29-30, 2012, Atlantic City, NJ, Proceedings.

  10. Y.-L. Lin, G. Jiang, J. Nor, and M. E.H. ElSayed. "Development of smart particles for effective gene silencing in epithelial cancer cells", Engineering Graduate Symposium, November 11, 2011, Ann Arbor, Michigan, Proceedings.

  11. Y.Y. Durmaz, Y.-L. Lin, and M. E.H. ElSayed. "Degradable, pH-sensitive, star vectors for cytoplasmic delivery of nucleic acids", Engineering Graduate Symposium, November 11, 2011, Ann Arbor, Michigan, Proceedings.

  12. O. Aydin, Y.Y. Durmaz, and M. E.H. ElSayed. "Synthesis of hybrid micelles for targeted delivery of chemotherapeutic agents for advanced prostate cancer therapy", Engineering Graduate Symposium, November 11, 2011, Ann Arbor, Michigan, Proceedings.

  13. Y.-L. Lin, G. Jiang, J. Nor, and M. E.H. ElSayed. "Development of smart particles for effective gene silencing in epithelial cancer cells", 35th Annual Symposium of Macromolecular Science and Engineering, October 27, 2011, Ann Arbor, Michigan, Proceedings.

  14. Y.Y. Durmaz, Y.-L. Lin, and M. E.H. ElSayed. "Degradable, pH-sensitive, star vectors for cytoplasmic delivery of nucleic acids", 35th Annual Symposium of Macromolecular Science and Engineering, October 27, 2011, Ann Arbor, Michigan, Proceedings. Frank E. Filisko Poster Award

  15. O. Aydin, Y.Y. Durmaz, and M. E.H. ElSayed. "Synthesis of hybrid micelles for targeted delivery of chemotherapeutic agents for advanced prostate cancer therapy", 35th Annual Symposium of Macromolecular Science and Engineering, October 27, 2011, Ann Arbor, Michigan, Proceedings.

  16. Y.Y. Durmaz, E. Vlaisavljevich, Z.Xu, and M. E.H. ElSayed. "Development of targeted nano-bubbles for ultrasound imaging and ablation of prostate cancer", 35th Annual Symposium of Macromolecular Science and Engineering, October 27, 2011, Ann Arbor, Michigan, Proceedings.

  17. J.D. Wang, N. Douville, S. Takayama, and M. E.H. ElSayed. "Development of physiologically relevant in vitro model of the blood-brain barrier", 35th Annual Symposium of Macromolecular Science and Engineering, October 27, 2011, Ann Arbor, Michigan, Proceedings.

  18. S.H. Medina, M.V. Chevliakov, Y.Y. Durmaz, D.S. Shewach, W.D. Ensminger, and M. E.H. ElSayed. "Development of enzyme-activated dendrimer-drug conjugates for selective liver cancer therapy", The 9th International Nanomedicine and Drug Delivery Symposium, October 15-16, 2011, Salt Lake City, Utah, Proceedings.

  19. C. Wallace, S.H. Medina, and M. E.H. ElSayed. "Effect of rhamnolipids on the integrity of Caco-2 cell monolayers", The 9th International Nanomedicine and Drug Delivery Symposium, October 15-16, 2011, Salt Lake City, Utah, Proceedings.

  20. Y.-L. Lin, G. Jiang, J. Nor, and M. E.H. ElSayed. "Development of smart particles for effective gene silencing in epithelial cancer cells", The 9th International Nanomedicine and Drug Delivery Symposium, October 15-16, 2011, Salt Lake City, Utah, Proceedings.

  21. Y.Y. Durmaz, Y.-L. Lin, and M. E.H. ElSayed. "Degradable, pH-sensitive, star vectors for cytoplasmic delivery of nucleic acids", The 9th International Nanomedicine and Drug Delivery Symposium, October 15-16, 2011, Salt Lake City, Utah, Proceedings.

  22. Y.Y. Durmaz, E. Vlaisavljevich, Z. Xu, and M. E.H. ElSayed. "Development of targeted nano-bubbles for ultrasound imaging and ablation of prostate cancer", The 9th International Nanomedicine and Drug Delivery Symposium, October 15-16, 2011, Salt Lake City, Utah, Proceedings.

  23. J.D. Wang, N. Douville, S. Takayama, and M. E.H. ElSayed. "Development of physiological 3D in vitro model of the blood-brain barrier", The 9th International Nanomedicine and Drug Delivery Symposium, October 15-16, 2011, Salt Lake City, Utah, Proceedings.

  24. Y.-L. Lin, G. Jiang, J. Nor, and M. E.H. ElSayed. "Smart particles silence chemo-resistance in epithelial cancer cells", The 3rd Controlled Release Society - Illinois Student Chapter Symposium, August 12, 2011, Chicago, Illinois, Proceedings. Second Place Poster Presentation Award

  25. S.H. Medina, M.V. Chevliakov, Y.Y. Durmaz, D.S. Shewach, W.D. Ensminger, and M. E.H. ElSayed. "Development of enzyme-activated nano-conjugates for hepatic cancer therapy", The 3rd Controlled Release Society - Illinois Student Chapter Symposium, August 12, 2011, Chicago, Illinois, Proceedings. Third Place Poster Presentation Award

  26. O. Aydin, Y.Y. Durmaz, and M. E.H. ElSayed. "Synthesis of hybrid micelles for targeted delivery of chemotherapeutic agents for advanced prostate cancer therapys", The 3rd Controlled Release Society - Illinois Student Chapter Symposium, August 12, 2011, Chicago, Illinois, Proceedings.

  27. Y.Y. Durmaz, Y.-L. Lin, and M. E.H. ElSayed. "Rational design and synthesis of "intelligent" star-shaped polymers for enhancing the intracellular delivery of nucleic acids", The 3rd Controlled Release Society - Illinois Student Chapter Symposium, August 12, 2011, Chicago, Illinois, Proceedings.

  28. J.D. Wang, N. Douville, S. Takayama, and M. E.H. ElSayed. "Development of physiological 3D in vitro model of the blood-brain barrier", The 3rd Controlled Release Society - Illinois Student Chapter Symposium, August 12, 2011, Chicago, Illinois, Proceedings.

  29. C. Wallace, S.H. Medina, and M. E.H. ElSayed. "Effect of rhamnolipids on the integrity of Caco-2 cell monolayers", The 3rd Controlled Release Society - Illinois Student Chapter Symposium, August 12, 2011, Chicago, Illinois, Proceedings.

  30. S.H. Medina, M.V. Chevliakov, Y.Y. Durmaz, D.S. Shewach, W.D. Ensminger, and M. E.H. El-Sayed. "Development of enzyme-activated dendrimer-drug conjugates for hepatic cancer therapy", Upper Midwest Biomaterials Day, May 12-13, 2011, Ann Arbor, Michigan, Proceedings.

  31. Y.-L. Lin, G. Jiang, J. Nor, and M. E.H. El-Sayed. "Development of "smart" particles for effective gene silencing", Upper Midwest Biomaterials Day, May 12-13, 2011, Ann Arbor, Michigan, Proceedings.

  32. Y. Y. Durmaz, Y.-L. Lin, and M. E.H. El-Sayed. "Rational design and synthesis of "intelligent" star-shaped polymers for enhancing the intracellular delivery of nucleic acids", Upper Midwest Biomaterials Day, May 12-13, 2011, Ann Arbor, Michigan, Proceedings.

  33. J. D. Wang, N. Douville, S. Takayama, and M. E.H. El-Sayed. "Development of a physiologically relevant in vitro model of the blood-brain barrier", Upper Midwest Biomaterials Day, May 12-13, 2011, Ann Arbor, Michigan, Proceedings.

  34. S.H. Medina, M.V. Chevliakov, Y.Y. Durmaz, D.S. Shewach, W.D. Ensminger, and M. E.H. El-Sayed. "Development of enzyme-activated dendrimer-drug conjugates for hepatic cancer therapy", Annual Symposium of the Cellular Biotechnology Training program, April 27, 2011, Ann Arbor, Michigan, Proceedings.

  35. Y.-L. Lin, G. Jiang, J. Nor, and M. E.H. El-Sayed. "Development of "smart" particles for effective gene silencing", Annual Symposium of the Cellular Biotechnology Training program, April 27, 2011, Ann Arbor, Michigan, Proceedings.

  36. Y. Y. Durmaz, Y.-L. Lin, and M. E.H. El-Sayed. "Rational design and synthesis of "intelligent" star-shaped polymers for enhancing the intracellular delivery of nucleic acids", Annual Symposium of the Cellular Biotechnology Training program, April 27, 2011, Ann Arbor, Michigan, Proceedings.

  37. J. D. Wang, N. Douville, S. Takayama, and M. E.H. El-Sayed. "Development of a physiologically relevant in vitro model of the blood-brain barrier", Annual Symposium of the Cellular Biotechnology Training program, April 27, 2011, Ann Arbor, Michigan, Proceedings.

  38. S.H. Medina, M.V. Chevliakov, Y.Y. Durmaz, D.S. Shewach, W.D. Ensminger, and M. E.H. El-Sayed. "Development of enzyme-activated dendrimer-drug conjugates for hepatic cancer therapy", 2011 Herbert D. Doan Nanotechnology Symposium, April 18, 2011, Ann Arbor, Michigan, Proceedings.

  39. Y.-L. Lin, G. Jiang, J. Nor, and M. E.H. El-Sayed. "Development of "smart" particles for effective gene silencing", 2011 Herbert D. Doan Nanotechnology Symposium, April 18, 2011, Ann Arbor, Michigan, Proceedings. Third Place Poster Presentation Award

  40. Y. Y. Durmaz, Y.-L. Lin, and M. E.H. El-Sayed. "Rational design and synthesis of "intelligent" star-shaped polymers for enhancing the intracellular delivery of nucleic acids", 2011 Herbert D. Doan nanotechnology Symposium, April 18, 2011, Ann Arbor, Michigan, Proceedings.

  41. J. D. Wang, N. Douville, S. Takayama, and M. E.H. El-Sayed. "Development of a physiologically relevant in vitro model of the blood-brain barrier", 2011 Herbert D. Doan Nanotechnology Symposium, April 18, 2011, Ann Arbor, Michigan, Proceedings. Second Place Poster Presentation Award

  42. S. H. Medina, M. Chevliakov, D. S. Shewach, W. D. Ensminger, and M. E.H. El-Sayed. "Development of enzyme-activated nanoconjugates for hepatic cancer therapy", College of Engineering Graduate Symposium, November 12, 2010, Ann Arbor, Michigan, Proceedings. Second Place Poster Presentation Award

  43. J. D. Wang, N. Douville, S. Takayama, and M. E.H. El-Sayed. "Development of a physiologically relevant in vitro model of the blood-brain barrier", College of Engineering Graduate Symposium, November 12, 2010, Ann Arbor, Michigan, Proceedings.

  44. Yen-Ling Lin, Guohua Jiang, and M. E.H. El-Sayed. "Development of smart particles for effective gene silencing in head and neck cancer", College of Engineering Graduate Symposium, November 12, 2010, Ann Arbor, Michigan, Proceedings.

  45. Yasemin Yuksel Durmaz, Yen-Ling Lin, and M. E.H. El-Sayed. "Development of star-shaped, pH-sensitive, membrane-destablizing polymer for cytoplasmic delivery of therapeutic nucleic acids", College of Engineering Graduate Symposium, November 12, 2010, Ann Arbor, Michigan, Proceedings.

  46. Jack Wang, Nick Douville, Shuichi Takayama, and Mohamed E.H. El-Sayed. "Development of a physiologically relevant in vitro model of the blood-brain barrier". Biomedical Engineering Society Meeting, October 6-9, 2010, Austin, Texas, Proceedings.

  47. S. Medina, M. Chevliakov, D. S. Shewach, W. D. Ensminger, and M. E.H. El-Sayed, "Development of enzyme-activated nanoconjugates for hepatic cancer therapy", Biomedical Engineering Society Meeting, October 6-9, 2010, Austin, Texas, Proceedings.

  48. S. Medina, V. Tekumalla, M. Chevliakov, D. S. Shewach, W. D. Ensminger, and M. E.H. El-Sayed, "N-Acetylgalactosamine functionalized dendrimers as liver-targeted drug carriers", Biomedical Engineering Society Meeting, October 6-9, 2010, Austin, Texas, Proceedings.

  49. Y-L. Lin, G. Jiang, and M. E.H. El-Sayed, "Development of "smart" particles for effective gene silencing in head & neck cancer", Biomedical Engineering Society Meeting, October 6-9, 2010, Austin, Texas, Proceedings.

  50. J. D. Wang, N. Douville, S. Takayama, and M. E.H. El-Sayed, "Quantitative analysis of molecular absorption of permeability markers into PDMS microfluidic channels", Controlled Release Society-Illinois Student Chapter Symposium, May 29, 2009, Chicago, Illinois, Proceedings.

  51. S. Grainger, J. Valencia-Serna, Y. Zhou, C. Deng, and M. E.H. El-Sayed, "Effect of therapeutic ultrasound on the penetration of model fluorescent nanoparticles into breast cancer spheroids", Controlled Release Society-Illinois Student Chapter Symposium, May 29, 2009, Chicago, Illinois, Proceedings.

  52. Y-L. Lin, G. Jiang, L. Birrell, and M. E.H. El-Sayed, "Development of "smart" particles for enhanced intracellular delivery of therapeutic nucleic acids", Controlled Release Society-Illinois Student Chapter Symposium, May 29, 2009, Chicago, Illinois, Proceedings. First Place Poster Award

  53. S. Medina, V. Tekumalla, and M. E.H. El-Sayed, "Uptake of N-acetyl galactosamine functionalized dendrimer carriers into hepatic cancer cells", Controlled Release Society-Illinois Student Chapter Symposium, May 29, 2009, Chicago, Illinois, Proceedings. Second Place Poster Award

  54. L. Birrell, and M. E.H. El-Sayed, "Effect of Clostridium Difficile toxin A on intestinal tight junctions", Midwest Biomedical Engineering Conference, April 3, 2009, Ann Arbor, MI, Proceedings. Poster Award Winner.

  55. J. D. Wang, N. Douville, S. Takayama, and M. E.H. El-Sayed, "Quantitative Evaluation of Molecular Absorption into PDMS Microfluidic Channels", Midwest Biomedical Engineering Conference, April 3, 2009, Ann Arbor, MI, Proceedings.

  56. S. Grainger, J. Valencia-Serna, S. Sunny, Y. Zhou, C. Deng, and M. E.H. El-Sayed, "Effect of ultrasound on the penetration of nanoparticles into breast cancer spheroids", Midwest Biomedical Engineering Conference, April 3, 2009, Ann Arbor, Michigan, Proceedings.

  57. Y-L. Lin, G. Jiang, L. Birrell, and M. E.H. El-Sayed, "In vitro evaluation of "smart" comb-like polymers for delivery of therapeutic nucleic acids", Midwest Biomedical Engineering Conference, April 3, 2009, Ann Arbor, Michigan, Proceedings.

  58. S. Medina, V. Tekumalla, and M. E.H. El-Sayed, "Cellular uptake of N-acetyl galactosamine functionalized PAMAM dendrimers into hepatic cancer cells", Midwest Biomedical Engineering Conference, April 3, 2009, Ann Arbor, Michigan, Proceedings.

  59. D. Wang, N. Douville, S. Takayama, and M. E.H. El-Sayed, "Quantitative analysis of molecular absorption into PDMS microfluidic channels", 14th International Symposium on Recent Advances in Drug Delivery Systems, February 15-18, 2009, Salt Lake City, Utah, Proceedings.

  60. S. Grainger, J. Valencia-Serna, Y. Zhou, C. Deng, and M. E.H. El-Sayed, "Effect of therapeutic ultrasound on penetration of nanoparticles into breast cancer spheroids", 14th International Symposium on Recent Advances in Drug Delivery Systems, February 15-18, 2009, Salt Lake City, Utah, Proceedings.

  61. Y-L. Lin, G. Jiang, L. Birrell, and M. E.H. El-Sayed, "Evaluation of "smart" comb-like polymers for delivery of therapeutic nucleic acids in vitro", 14th International Symposium on Recent Advances in Drug Delivery Systems, February 15-18, 2009, Salt Lake City, Utah, Proceedings.

  62. S. H. Medina, V. Tekumalla, and M. E.H. El-Sayed, "Development of N-acetyl galactosamine functionalized PAMAM dendrimers for targeted drug delivery to hepatic cancer cells", 14th International Symposium on Recent Advances in Drug Delivery Systems, February 15-18, 2009, Salt Lake City, Utah, Proceedings.

  63. S. H. Medina, R. Stender, P. Boucher, D. Shewach, W. Ensminger, and M. E. H. El-Sayed, "In vivo biodistribution of PAMAM dendrimers in solid tumor models", University of Michigan Engineering Graduate Symposium, November 7, 2008, Ann Arbor, Michigan, Proceedings.

  64. Y. Lin, G. Jiang, L. Birrell, and M. E. H. El-Sayed, "In vitro evaluation of "smart" polymeric carriers for delivery of nucleic acid drugs", University of Michigan Engineering Graduate Symposium, November 7, 2008, Ann Arbor, Michigan, Proceedings.

  65. Y. Lin, Khalil Khanafer, and M. E. H. El-Sayed, "Quantitative evaluation of the effect of poly (amidoamine) dendrimers on the porosity of Caco-2 cell monolayers", University of Michigan Engineering Graduate Symposium, November 7, 2008, Ann Arbor, Michigan, Proceedings.

  66. S. Grainger, Y. Zhou, C. Deng, and M. E. H. El-Sayed, "Effect of ultrasound on penetration of nanoparticles into breast cancer spheroids", University of Michigan Engineering Graduate Symposium, November 7, 2008, Ann Arbor, Michigan, Proceedings. 2nd Place, Biodevices & Biophysics Poster Session.

  67. D. Wang, N. Douville, S. Takayama, and M. E. H. El-Sayed, "Quantitative analysis of molecular absorption into PDMS micorfluidic channels", University of Michigan Engineering Graduate Symposium, November 7, 2008, Ann Arbor, Michigan, Proceedings.

  68. S. Koski, M. Mayer, and M. E. H. El-Sayed, "Mechanistic investigation of the interaction between endosomal lipid membrane and cationic polymers", University of Michigan Engineering Graduate Symposium, November 7, 2008, Ann Arbor, Michigan, Proceedings.

  69. G. Jiang, L. Birrell, Y-L. Lin, and M. E. H. El-Sayed, "Smart" polymeric carriers for enhanced intracellular delivery of nucleic acid drugs, DOD-Era of Hope Meeting, June 25-28, 2008, Baltimore, Maryland, Proceedings

  70. M. E.H. El-Sayed, E. M. Bulger, A. S. Hoffman, and P. S. Stayton, "Development and evaluation of "smart" polymer-nucleic acid complexes", The Society for Biomaterials Annual Meeting, April 26-29, 2006, Pittsburgh, Pennsylvania, Proceedings

  71. M. E.H. El-Sayed, A. S. Hoffman, and P. S. Stayton, "Development of pH-responsive, endosomal membrane-disruptive, and glutathione-reactive polymeric carriers for enhanced intracellular delivery of therapeutic molecules", 32nd Annual Meeting and Exposition of the Controlled Release of Bioactive Materials, June 18 - 22, 2005, Miami, Florida, Proceedings

  72. M. El-Sayed, M. Ginski, C. A. Rhodes, and H. Ghandehari, "Influence of charge of poly (amidoamine) dendrimers on Caco-2 cell monolayers", 17th Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, November 10-14, 2002, Toronto, Ontario, Canada, Proceedings

  73. M. El-Sayed, M. Ginski, C. Rhodes, and H. Ghandehari, Transport of Poly amidoamine (PAMAM) Dendrimers Across Caco-2 Cell Monolayers. 16th Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists (AAPS), October 21-25, 2001, Denver, Colorado, Proceedings

  74. M. El-Sayed, M. Ginski, C. Rhodes, and H. Ghandehari, Transport of poly amidoamine (PAMAM) dendrimers across Caco-2 cell monolayers, 21st Annual Graduate Research Association of Students in Pharmacy (GRASP) Conference, June 8-10, 2001, Storrs, Connecticut, Proceedings

  75. M. El-Sayed, M. Ginski, C. Rhodes, and H. Ghandehari, Transepithelial transport of Poly amidoamine (PAMAM) dendrimers, University of Maryland, School of Pharmacy research day, May 8, 2001, Baltimore, Maryland, Proceedings

  76. M. El-Sayed, M. Ginski, C. Rhodes, and H. Ghandehari, Potential of Poly amidoamine (PAMAM) dendrimers as oral drug delivery systems, 23rd Annual Graduate Research Conference, April 18, 2001, Baltimore, Maryland, Proceedings

  77. M. El-Sayed, M. Ginski, C. Rhodes, and H. Ghandehari, Permeability and Absorption Enhancing Properties of Cationic Poly Amidoamine (PAMAM) Dendrimers Across Caco-2 Cell Monolayers, 8th Annual Student Poster Night - Philadelphia Pharmaceutical Forum, March 15th, 2001, Ambler, Philadelphia, Proceedings

  78. M. El-Sayed, M. Ginski, C. Rhodes, and H. Ghandehari, Transport of cationic Poly amidoamine (PAMAM) dendrimers across Caco-2 cell monolayers, 10th International Symposium On Recent Advances In Drug Delivery Systems, February 19-22, 2001, Salt Lake City, Utah, Proceedings

  79. H. Ghandehari, M. F. Kiani, M. Naimark, M. El-Sayed, F. Tajarobi, J. Polli, and B. Rege, Transendothelial and -epithelial transport of poly (amidoamine) (PAMAM) dendrimers, 2000 Biomedical Engineering Society Annual Fall Meeting, October 12-14, 2000, Seattle, Washington, Proceedings

  80. H. Ghandehari, M. El-Sayed, M. Haider, A. Nagarsekar, A. Nan, and F. Tajarobi, Intelligent Biomaterials: Constructs For The Next Generation Of Drug Delivery Systems. First International Conference for Pharmaceutical Industry, September 27-29, 2000, Cairo, Egypt, Proceedings

  81. M. El-Sayed, M. F. Kiani, M. Naimark, and H. Ghandehari, Transport of macromolecular drug carriers across microvascular beds, 220th American Chemical Society National Meeting, August 20-24, 2000, Washington, D.C., Proceedings

  82. M. El-Sayed, M. F. Kiani, M. Naimark, and H. Ghandehari, Influence of polymeric structural features of Poly (amidoamine) (PAMAM) dendrimers on their transport across biological barriers, 59th Prague Meeting on Macromolecules, July 17 - 20, 2000, Prague, Czech Republic, Proceedings

  83. F. Tajarobi, M. El-Sayed, B. Rege, J. Polli and H. Ghandehari, Transport of poly (amidoamine) (PAMAM) dendrimers across Madin Darby Canine Kidney (MDCK) cell lines, 59th Prague Meeting on Macromolecules, July 17 - 20, 2000, Prague, Czech Republic, Proceedings

  84. M. El-Sayed, M. F. Kiani, M. Naimark, and H. Ghandehari, Influence of size, molecular weight and geometry on the extravasation of polymeric drug carriers across the microvascular endothelium, 27th International Symposium on Controlled Release of Bioactive Materials (CRS), July 7 - 13, 2000, Paris, France, Proceedings

  85. M. El-Sayed, M. F. Kiani, M. Naimark, and H. Ghandehari, Extravasation of poly (amidoamine) (PAMAM) dendrimers across microvascular network endothelium, 20th Annual Graduate Research Association of Students in Pharmaceutics (GRASP) Conference, June 2-4, 2000, Baltimore, Maryland, Proceedings. Best Podium Presentation Award.

  86. M. El-Sayed, M. F. Kiani, M. Naimark, and H. Ghandehari, Extravasation of Poly amidoamine (PAMAM) dendrimers across microvascular network endothelium, University of Maryland, School of Pharmacy research day, May 9, 2000, Baltimore, Maryland, Proceedings

  87. M. El-Sayed, M. F. Kiani, M. Naimark, A. H. Hikal, and H. Ghandehari, Influence of size, molecular weight and geometry on the extravasation of polymeric drug carriers across the microvascular endothelium, 22nd Annual Graduate Research Conference, April 19, 2000, Baltimore, Maryland, Proceedings. Best Poster Presentation Award.

  88. M. El-Sayed, M. F. Kiani, M. Naimark, A. H. Hikal, and H. Ghandehari, Extravasation of poly (amidoamine) dendrimers across the microvascular network endothelium, 7th Annual Student Poster Night - Philadelphia Pharmaceutical Forum, March 9th, 2000, Ambler, Philadelphia, Proceedings. Charles A. Stevens Memorial Award.

  89. M. El-Sayed, M. F. Kiani, M. Naimark, A. H. Hikal, and H. Ghandehari, Extravasation of poly (amidoamine) dendrimers across the microvascular network endothelium, Gordon Conference, February 20-25, 2000, Ventura, California. Selected for oral presentation session.

  90. M. El-Sayed, M. F. Kiani, M. Naimark, and H. Ghandehari, Extravasation of poly (amidoamine) dendrimers across the microvascular network endothelium, 14th Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists (AAPS), November 14-18, 1999, New Orleans, Louisiana, Proceedings

  91. M. El-Sayed, M. F. Kiani, M. Naimark, A. H. Hikal, and H. Ghandehari, Extravasation of poly (amidoamine) dendrimers across the microvascular network endothelium, 2nd Annual meeting of the American Association of Pharmaceutical Scientists - Southern Regional Discussion Group (AAPS-SRDG), May 20-21, 1999, Monroe, Louisiana, Proceedings. Best Podium Presentation Award.

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