Biomaterials: The following are some of the biomaterials-related research areas undertaken in the Takayama Lab: Lam, M. T.; Huang, Y.-C.; Birla, R. K.; Takayama, S. “Microfeature guided skeletal muscle tissue engineering for highly organized 3-dimensional free-standing constructs” Biomaterials 2009, 30, 1150-1155. Mills, K. L.; Zhu, X.; Takayama, S.; Thouless, M. D. “The mechanical properties of a surface-modified layer on poly(dimethylsiloxane)” J. Mater. Res. 2008, 23, 37-48. Lam, M.T.; Clem, W.; Takayama, S. “Dynamic microtopography for reversible on-demand cell alignment” Biomaterials 2008, 29, 1705-1712.

Fan, C. Y.; Tung, Y.-C.; Takayama, S.; Meyhofer, E.; Kurabayashi, K. “Electrically Programmable Surfaces for Configurable Patterning of Cells” Adv. Mater. 2008, 20, 1418-1423.

Mehta, G.; Kiel, M. J.; Lee, J. W.; Kotov, N.; Linderman, J. J.; Takayama, S. “Polyelectrolyte-Clay-Protein Layer Films on Microfluidic PDMS Bioreactor Surfaces for Primary Murine Bone Marrow Cultures”Adv. Funct. Mater. 2007, 17, 2701-2709.

Huh, D.; Mills, K.L.; Zhu, X.Y.; Burns, M.A.; Thouless, M.D.; Takayama, S. “Tuneable elastomeric nanochannels for nanofluidic manipulation” Nature Materials 2007, 6, 424-428.

Lam, M. T.; Sim, S.; Zhu, X.; Takayama, S. “The Effect of Continuous Wavy Micropatterns on SIlicone Substrates on the ALignment of Skeletal Muscle Myoblasts and Myotbues” Biomaterials. 2006 27, 4340-4347.

Wu, J. M.; Chung, Y.; Belford, K. J.; Smith, G. D.; Takayama, S.; Lahann, J. “A surface-modified sperm sorting device with long-term stability” Biomed. Microdev. 2006, 8, 99-107.

Zhu, X.; Mills, K. L.; Peters, P. R.; Bahng, J. H.; Liu E. H.; Shim, J.; Naruse, K.; Csete, M. E.; Thouless, M. D.; Takayama, S. “Fabrication of Reconfigurable Protein Matrices by Cracking” Nat. Mater. 2005, 4, 403-406.

Futai, N.; Gu, W.; Takayama, S. “Rapid Prototyping of Microstructures with Bell-Shaped Cross-Sections and Its Application to Deformation-Based Microfluidic Valves” Adv. Mater. 2004, 16, 1320-1323.

Jiang, X.; Takayama S.; Qian, X.; Ostuni, E.; Wu, H.; Bowden, N.; LeDuc, P.; Ingber, D. E.; Whitesides, G. M. “Controlling Mammalian Cell Spreading and Cytoskeletal Arrangement with Conveniently Fabricated Continuous Wavy Features on Poly(dimethylsiloxane)” Langmuir, 2002; 18, 3273.

Holmlin, R. E.;Chen, X.; Chapman, R.; Takayama, S.; Whitesides, G. M. "Zwitterionic SAMs that Resist Nonspecific Adsorption of Protein from Aqueous Buffer" Langmuir, 2001, 17, 2841-2850.

Whitesides, G.M.; Ostuni, E.; Takayama, S.; Jiang, X "Soft Lithography for Biology" Ann. Rev. Biomed. Eng. 2001, 3, 335-373.

Ostuni, E; Chapman, R. G.; Holmlin, R. E.; Takayama, S.; Whitesides, G. M. "A Survey of Structure-Property Relationships of Surfaces that Resist the Adsorption of Proteins" Langmuir, 2001, 17, 5605-5620.

Chapman, R. G.; Ostuni, E.; Takayama, S.; Holmlin, R. E.; Yan, L.; Whitesides, G. M. "Surveying for Surfaces that Resist the Adsorption of Proteins" J. Am. Chem. Soc. 2000, 122, 8303-8304.