Biosensing: The following are some of the biosensing research areas undertaken in the Takayama Lab: Jovic, A.; Howell, B.; Takayama, S. “Timing is Everything: Using Fluidics to Understand the Role of Temporal Dynamics in Cellular Systems” Microfluidics Nanofluidics 2009, in press. Huh, D; Fujioka, H.; Tung, Y.-C.; Futai, N.; Paine, R.; Grotberg, J. B.; Takayama, S. “Acoustically Detectable Cellular-Level Lung Injury Induced by Fluid Mechanical Stresses in Microfluidic Airway Systems”J. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 18886-18891.

Mehta, G.; Mehta, K.; Sud, D.; Song, J.W.; Bersano-Begey, T.; Futai, N.; Heo, Y.S.; Mycek, M.-A.; Linderman, J.J.; Takayama, S. “Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture” Biomedical Microdevices 2007, 9, 123-134.

Sud, D.; Mehta, G.; Mehta, K.; Linderman, J. J.; Takayama, S.; Mycek, M.-A. “Optical Imaging in Microfluidic Bioreactors Enable Oxygen Monitoring for Continuous Cell Culture” Opt. Lett. 2006,11, Art. No. 050504.

Sawano, A.; Takayama, S.; Matsuda, M.; Miyawaki, A. “Lateral Propagation of EGF Signaling after Local Stimulation Is Dependent on Receptor Density” Dev. Cell, 2002, 3, 245-257.