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Ann Arbor, MI – Lonnie D. Shea has been named professor and chair of the University of Michigan Department of Biomedical Engineering (BME), effective September 1, 2014.
Shea, who earned his PhD from U-M in 1997, was recruited from Northwestern University’s Department of Chemical and Biological Engineering, where he has served on the faculty since 1999. He is an internationally recognized researcher at the interface of regenerative medicine, drug and gene delivery, and immune tolerance, whose focus is controlling the local microenvironment for directing tissue growth or regeneration. His projects include ovarian follicle maturation for treating infertility, islet transplantation for diabetes therapies, nerve regeneration for treating paralysis, autoimmune diseases and allogeneic cell transplantation, and cancer diagnostics. He is also developing and applying systems biology approaches to molecularly dissect tissue formation and identify key drivers of normal and abnormal growth.
Shea has received funding from the National Institutes of Health (NIH), National Science Foundation (NSF) and multiple foundations; has published more than 150 manuscripts on his research; and has numerous inventions to his credit, among them a cellular assay with which he can measure the activity of numerous transcription factors within the cell that reveal key signaling pathways as cells differentiate and develop in his customized 3D cultures.
In addition to his research and teaching responsibilities at Northwestern, Shea served as director of its NIH Biotechnology Training Grant and was a member of its Institute for BioNanotechnology in Medicine. He is a fellow of the American Institute of Medical and Biological Engineering (AIMBE), a standing member of the Biomaterials and Bionterfaces study section at NIH, and a member of the editorial boards for Molecular Therapy, Biotechnology and Bioengineering, and Drug Delivery and Translational Research.
Shea completed his BS and MS degrees in chemical engineering at Case Western Reserve University. He received his PhD in chemical engineering and scientific computing from U-M in 1997, working with BME and Chemical Engineering Professor Jennifer Linderman. He then served as a postdoctoral fellow with Professor David Mooney in the Department of Biologic and Materials Science in the U-M Dental School. In 2000, Shea received a CAREER Award, the NSF’s most prestigious award in support of junior faculty who exemplify outstanding research and teaching.
Shea is enthusiastic about returning to his alma mater and continuing the momentum of the BME department, which underwent significant growth under former Chair Douglas C. Noll. When Noll stepped down in late 2013, the department had doubled its faculty from 11 to 22, received a $20 million endowment through the U-M Coulter Partnership for Translational Biomedical Engineering Research, and been restructured into a joint department of the College of Engineering and medical school.
Shea, who will have the opportunity to hire another 10 faculty, says he is eager to continue on this trajectory. Among his goals are “inspiring students toward accomplishments they never imagined possible” and “fostering research that doesn’t focus on publishing the next paper but on changing the way researchers and clinicians approach the problem.”
Interim Chair Ronald G. Larson feels Shea is more than up to the challenge. He says, “Lonnie is exceptionally talented at working at the interface between engineering and medicine. I believe he will be a superb role model for the department and will help vault it into the top ranks of national and international leadership in biomedical engineering.”
It’s a little bit later than usual, but we are excited to share with you the spring/summer 2014 edition of the University of Michigan Biomedical Engineering News. This issue provides an in-depth look at our cutting edge research and the people challenging conventions throughout our discipline.
We are pleased to offer our publication in a digital edition for simple viewing from a desktop browser or your favorite mobile device.
ROW BLUE! From July 2-6, a squad of Michigan rowers will represent the Block M on the River Thames, an hour west of London. Recent U-M BME grad Alex Crawford and six more of the other twelve U-M oarsmen competing are engineering majors! More than 100,000 spectators, including much of the Royal Family, will be in attendance. To read the full Michigan Engineering article see: http://umicheng.in/1iQLDL9
An article that BME Associate Professor David Sept authored with Ron Bose and other collaborators from Washington University in St. Louis was selected as a 2013 paper of the year in the Journal of Biological Chemistry. It won in the signal transduction category for providing the first structural characterization of HER2-HER3 heterodimers used in cancer therapy. The paper is titled Carboxyl Group Footprinting Mass Spectrometry and Molecular Dynamics Identify Key Interactions in the HER2-HER3 Receptor Tyrosine Kinase Interface. It can be accessed at www.jbc.org/site/bestoftheyear/.
Tags: Awards, Carboxyl Group Footprinting, David Sept, Journal, Journal of Biological Chemistry, Mass Spectrometry, Molecular Dynamics, Washington University in St. Louis
Posted in All News, Faculty News
U-M BME Professor Scott Hollister and U-M Mott Dr. Glenn Green have done it again by teaming up to design and implant a 3-D printed tracheal splint, saving another child’s life. Garrett Peterson, only 18 months old, out of Layton, Utah, underwent an emergency surgery that would install two pieces of flexible tubing around his trachea to keep the airways open as he grows and develops. Eventually they will dissolve as Garrett’s own windpipe becomes stronger. Hollister and Green had to seek an emergency waiver from the FDA to perform the surgery. NPR has done a story on their website and “Morning Edition,” titled “Doctors Use 3-D Printing To Help A Baby Breathe“ with more information on this amazing accomplishment.
Image by: Nicole Haley/University of Michigan Health System
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