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Artificial Organs

Core Faculty

Joseph L. Bull, Ph.D.
Arthur F. Thurnau Professor, Biomedical Engineering
Professor, Biomedical Engineering

2212 Lurie Biomedical Engineering
1101 Beal Avenue
Ann Arbor, MI 48109-2110

Phone: (734) 647-5395
Fax: (734) 647-4834

More Info: Professor Bull's research group, the Biotransport Research Lab, is focused on fundamental and applied aspects of biological flow and transport, primarily in the cardiovascular and pulmonary systems and related biomedical devices. Major research areas for the lab include gas embolotherapy, e.g. using gas bubbles formed by acoustic droplet vaporization to selectively block blood flow or deliver drugs to tumors; ultrasound decorrelation flow and stress measurement; biofluid mechanics of soft tissue and edema; biological micro- and nano-fluidic devices for therapy and diagnostics; artificial lungs; and vascular mechanics to inform and guide clinical treatment of aneurysms and dissections.

Research Areas: Biomechanics, Artificial Organs, Bio-MEMS and Microfluidics, Bio-Nanotechnology, Biofluids.

James B. Grotberg, Ph.D., M.D.
Professor, Biomedical Engineering
Professor, Surgery

2123 Carl A. Gerstacker Building
2200 Bonisteel Boulevard
Ann Arbor, MI 48109-2099

Phone: (734) 936-3834
Fax: (734) 936-1905

More Info: Dr. Grotberg's research group, the Biofluid Mechanics Research Laboratory, is dedicated to several aspects of respiratory and cardiovascular function, diseases, diagnostics, and therapies. Current and recent topics include lung airway dynamics in asthma and emphysema, surfactant and drug delivery to the lung of adults with cystic fibrosis as well as to prematurely born neonates, lung tissue interactions and damage from two phase flow in airways, development of an artificial implantable lung as well as an artificial placenta. Members of the lab are engaged in both experimentation and mathematical theory, and we collaborate with clinical investigators.

Research Areas: Biomechanics, Artificial Organs, Biofluids.

Ariella Shikanov, Ph.D.
Assistant Professor, Biomedical Engineering
Assistant Professor, Macromolecular Science and Engineering

2126 Lurie Biomedical Engineering
1101 Beal Avenue
Ann Arbor, MI 48109-2110

Phone: (734) 615-3360

More Info: The research of Dr. Shikanov translates the principles of biomaterials science and tissue engineering to the field of reproductive biology. The goal of this research is to preserve fertility in cancer patients by creating an artificial environment that supports in vitro folliculogenesis and subsequent growth of an artificial ovary. Sustaining ovarian follicle culture is a bioengineering challenge due to the unique spatio-temporal dynamics with respect to the developmental stage of the ovarian follicle. Design of tunable and functional hydrogels that support and direct biological functions can address this challenge. Other research projects include tumor engineering and reproductive toxicology. The former aims to screen anticancer drug efficacy using 3D hydrogel-based culture systems of in vitro grown tumors. The latter predicts and correlates the effects of various toxins on reproductive system in a biologically relevant environment mimicking in vivo conditions. This approach allows omitting time and resource consuming animal experiments in the screening process.

Research Areas: Artificial Organs, Biomaterials, Drug Delivery and Therapeutics, Tissue Engineering and Regenerative Medicine.

Jointly Appointed Faculty

Kate F. Barald, Ph.D.
Professor, Biomedical Engineering
Director, Michigan NIH-PREP Program
Program in Biomedical Sciences,
Neuroscience, CMB, Organogenesis, Cancer Biology
Director, Research Responsibility and Ethics Programs in the STEM Disciplines

3053 BSRB
109 Zina Pitcher Place
Ann Arbor, MI 48109-2200

Phone: (734) 647-3376
Fax: (734) 763-1166

Research Areas: Artificial Organs, Bio-MEMS and Microfluidics, Biomaterials, Molecular and Cellular Biomechanics, Neural Engineering, Tissue Engineering and Regenerative Medicine.

Emeritus Faculty

There are no Emeritus BME Faculty in Artificial Organs