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Biomedical Ultrasonics and Image-Guided Therapy

Core Faculty


Charles A. Cain, Ph.D.
Founding Chair, Biomedical Engineering
Professor, Biomedical Engineering
Professor, Electrical Engineering & Computer Science
Richard A. Auhll Professor, Engineering

2121 Carl A. Gerstacker Building
2200 Bonisteel Boulevard
Ann Arbor, MI 48109-2099

Phone: (734) 764-9589
Fax: (734) 936-1905
Email: cain@eecs.umich.edu
Website: www.histotripsy.umich.edu


More Info: For the past five years, Professor Cain's research team has been developing a new technique called "Histotripsy" which is a non-invasive ultrasonic tissue fractionation approach for the treatment of benign disease and cancer. Histotripsy results in localized tissue removal with sharp boundaries, which they use to remove cardiac tissue in treatment of congenital heart disease. In bulk tissue, histotripsy produces mechanical fragmentation of tissue resulting in a liquefied core with very sharply demarcated boundaries. Histology demonstrates that treated tissue within the lesion is fragmented to subcelluar level surrounded by an almost imperceptibly narrow margin of cellular injury. Histotripsy has vast clinical applications where precise tissue ablation and removal are needed (e.g., tumor treatment).


Research Areas: Biomedical Imaging, Biomedical Ultrasonics and Image-Guided Therapy.


Cheri X. Deng, Ph.D.
Associate Professor, Biomedical Engineering

2111 Carl A. Gerstacker Building
2200 Bonisteel Boulevard
Ann Arbor, MI 48109-2099

Phone: (734) 936-2855
Email: cxdeng@umich.edu
Website: sitemaker.umich.edu/denglab


More Info: Professor Deng's lab focuses on research and development in the field of biomedical ultrasound. The objective of the lab is to obtain improved understanding of the processes and mechanism involved in ultrasound interaction with biological systems for the purpose of developing efficient techniques for diagnosis and treatment of human diseases. Specific research projects include ultrasound mediated drug and gene delivery for cancer treatment and gene therapy, high intensity focus ultrasound ablation of cardiac arrhythmias such as atrial fibrillation, as well as quantitative ultrasound imaging for improved pancreatic cancer detection.


Research Areas: Biomedical Imaging, Biomedical Ultrasonics and Image-Guided Therapy, Drug Delivery and Therapeutics.


Zhen Xu, Ph.D.
Assistant Professor, Biomedical Engineering

2107 Carl A. Gerstacker Building
2200 Bonisteel Boulevard
Ann Arbor, MI 48109-2099

Phone: (734) 647-4961
Fax: (734) 939-1905
Email: zhenx@umich.edu
Website: www.bme.umich.edu/labs/xulab/


More Info: Dr. Xu's research group focuses on developing image-guided therapy for cardiovascular applications. Her lab has been developing non-invasive therapy methods to remove pathological blood clots, which are the key mechanism behind many cardiovascular diseases including stroke and deep vein thrombosis. This new method can locally destroy clot without any incision or catheter insertion, and has potential to greatly reduce the complications of current clot remove methods. Her lab is also working on non-invasive fetal therapy that may prevent certain congenital diseases from developing before birth.


Research Areas: Biomedical Imaging, Biomedical Ultrasonics and Image-Guided Therapy.



Jointly Appointed Faculty


James Balter, Ph.D.
Professor, Radiation Oncology
Professor, Biomedical Engineering

B2C490 UH
1500 East Medical Center Drive
Ann Arbor, MI 48109-0010

Phone: (734) 936-4309
Fax: (734) 936-7859
Email: jbalter@umich.edu
Website: sitemaker.umich.edu/balterresearch/home


Research Areas: Biomedical Imaging, Biomedical Ultrasonics and Image-Guided Therapy, Functional and Molecular Imaging.


Paul L. Carson, Ph.D.
Professor, Biomedical Engineering
BRS Collegiate Professor, Radiology
Associate Director, Basic Radiological Sciences Division

3218C Medical Science Building I, B Wing
1301 Catherine Street
Ann Arbor, MI 48109-5667

Phone: (734) 763-5884
Fax: (734) 764-8541
Email: pcarson@umich.edu
Website: Click Here


Research Areas: Bio-Nanotechnology, Biomedical Imaging, Biomedical Optics, Biomedical Ultrasonics and Image-Guided Therapy, Drug Delivery and Therapeutics, Functional and Molecular Imaging.


J. Brian Fowlkes, Ph.D.
Professor, Radiology
Professor, Biomedical Engineering

3226C Medical Science Building I, B Wing
1301 Catherine Street
Ann Arbor, MI 48109-5667

Phone: (734) 763-5882
Fax: (734) 764-8541
Email: fowlkes@umich.edu


Research Areas: Biomedical Imaging, Biomedical Ultrasonics and Image-Guided Therapy.


Renny T. Franceschi, Ph.D.
Professor of Dentistry and Biological Chemistry, University of Michigan School of Dentistry
Professor, Biomedical Engineering

3328 School of Dentistry
1011 North University Avenue
Ann Arbor, MI 48109-1078

Phone: (734) 763-7381
Fax: (734) 763-5503
Email: rennyf@umich.edu


Research Areas: Biomedical Ultrasonics and Image-Guided Therapy, Molecular and Cellular Biomechanics, Tissue Engineering and Regenerative Medicine.


William W. Roberts, M.D.
Associate Professor, Urology
Associate Professor, Biomedical Engineering

3879 Taubman Center
1500 East Medical Center Drive
Ann Arbor, MI 48109-5338

Phone: (734) 647-2010
Fax: (734) 936-9127
Email: willrobe@umich.edu


Research Areas: Biomedical Ultrasonics and Image-Guided Therapy.



Emeritus Faculty


There are no Emeritus BME Faculty in Biomedical Ultrasonics and Image-Guided Therapy